Approach to the Case

[…] (most of these patients have TP from DIC) DIC + + TMA ( TTP, HUS) + + Valve hemolysis + Not typically associated with TP Spur […]

Key Takeaways

[…] liver disease and warfarin reversal Replacement fluid: plasmapheresis for thrombotic thrombocytopenia purpura ( TTP) Bleeding or disseminated intravascular coagulation (DIC) Correction of single factor deficiencies when […]

Labs

[…] reversal As a replacement fluid therapeutic plasma exchange for thrombotic thrombocytopenic purpura ( TTP). In bleeding with INR >1.5 or disseminated intravascular coagulopathy. For correction of […]

Knowledge Check

[…] develop anemia, not thrombocytopenia. c Pernicious anemia d Hypothyroidism e Thrombotic microangiopathy (e.g., TTP) Which is the preferred method for diagnosing babesiosis: a PCR b Thin […]

Hemolysis Case 1

[…] Which peripheral smear belongs to this patient? a A Warm AIHA b B TTP c C Spur cell anemia d D Sickle cell disease TheBloodProject-logo-initials TheBloodProject-logo-initials […]

Differential Diagnosis of Thrombocytopenia According to Mechanism

[…] Megaloblastic anemia Chemotherapy Increased consumption/destruction: Consumption: Thrombotic microangiopathy including: Thrombotic thrombocytopenic purpura ( TTP) Atypical hemolytic uremic syndrome (aHUS) Disseminate intravascular hemolysis (DIC) Extracorporeal devices Antiphospholipid […]

References

[…] management Hematology Am Soc Hematol Educ Program. 2018;2018(1):530-538 Clinical and laboratory diagnosis of TTP: an integrated approach Clinical practice guidelines ISTH guidelines for treatment of thrombotic […]