Hemolysis Case 1
Which of the above red blood cells most closely resembles our patient’s (RBC 2 is normal)?
Correct. The MCHC is increased, indicating loss of central pallor and “hyperchromia”, aka spherocyte.
Name 2 or 3 conditions associated with an elevated MCHCClick for Answer
The patient’s CBC was normal one year ago. What is the most likely diagnosis?Click for Answer
Is the reticulocyte count appropriate or inappropriate for the degree of anemia?
Though it is preferable to look at the ABSOLUTE retic count, which is not provided here.
Why would the retic count be inappropriate in the setting of hemolysis?Click for Answer
What would you expect the blood smear to show?Click for Answer
The DAT was positive in this patient. Her diagnosis was indeed warm autoimmune hemolytic anemia:
Which peripheral smear belongs to this patient?
Spur cell anemia
Sickle cell disease
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