Hemolysis Case 1

Which of the above red blood cells most closely resembles our patient’s (RBC 2 is normal)?

a
RBC 1
b
RBC 2
c
RBC 3
Correct. The MCHC is increased, indicating loss of central pallor and “hyperchromia”, aka spherocyte.

Is the reticulocyte count appropriate or inappropriate for the degree of anemia?

a
Appropriate
b
Inappropriate
Though it is preferable to look at the ABSOLUTE retic count, which is not provided here.

The DAT was positive in this patient. Her diagnosis was indeed warm autoimmune hemolytic anemia:

Which peripheral smear belongs to this patient?

a
A
Warm AIHA
b
B
TTP
c
C
Spur cell anemia
d
D
Sickle cell disease
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