Welcome to the CAD Topic Module
Cold Agglutinin Disease (CAD) is a rare autoimmune hemolytic anemia caused by cold-reactive antibodies that lead to red blood cell destruction. This module brings together everything you need to know about CAD in one place.
Our Topic Modules are designed as 360-degree, one-stop hubs for hematology diseases—far more comprehensive than what you’ll find in textbooks or standard online references.

Two features set these modules apart:
1. Breadth of Content
We go beyond the core clinical domains of epidemiology, pathophysiology, diagnosis, and treatment. You’ll also find topics rarely gathered in one place, e.g.:
- History of medicine
- Eponyms
- Evolutionary perspectives
- Comparative physiology
- Patient narratives
- Ethical considerations
2. Variety of Formats
Learning isn’t limited to text. We use a multimedia approach that incorporates diverse formats rarely found together in a single resource, including:
- Infographics
- Podcasts
- AI-generated explainer videos
- Expert video lectures
- Peripheral smears
- Case studies
In short, our distinctiveness lies across two axes: the breadth of content and the diversity of presentation.
We hope you enjoy exploring this resource—and we welcome your feedback to help us keep improving the learning experience.
Co-Editors:
Catherine Broome
Ishan J. Tatake
Contributors:
William C Aird
Kevin Barnum
Azra Borogovac
Brian J Carney
Spero Cataland
Shruti Chaturvedi
John Chilton
James N George
Ashley Hallice
Marlene Healy
Contributors:
Kristin LaFollette
Helen Osborne
Flora Payvandi
Bentley Rodrigue
Zachary R Schoepflin
Marie Scully
Ishan J Tatake
Lester Zamora
X. Long Zheng
Developed with support from an unrestricted educational grant from Recordati.