- About this Module
- Co-Editors Welcome
- Introduction
- The History of VWD
- Definitions & Classification
- Pathophysiology
- Evolutionary Medicine
- Epidemiology
- Clinical Presentation
- Diagnosis
- Treatment
- Special Situations in VWD
- Acquired von Willebrand Syndrome
- Longitudinal Care
- Patient Resources
- Clinician Communication
- Humanities, Meaning & Experience
- Journal Club
- Review Library
- Clinical Practice Guidelines
- Beyond the Guidelines
- Clinical Cases
- Media Library
Diagnostic Approach as Localization
Diagnose VWD by localizing failed hemostatic function, not by reacting to one abnormal test
First-Line Testing
What VWF antigen, platelet-dependent activity, factor VIII, CBC, PT, and aPTT can and cannot tell you
Second-Line VWD Testing
How multimers, collagen binding, RIPA, FVIII binding, VWFpp, and genetics refine diagnosis
Interpreting VWF Labs Relationally
Why VWF results make sense only in relation to one another and to the bleeding phenotype
Interpreting Bleeding Assessment Tools
Use BATs to structure bleeding history without worshipping the score
Laboratory Pitfalls and Repeat Testing
Why VWF testing is shaped by timing, stress, pregnancy, inflammation, assay limits, and repeat testing
Diagnostic Test Atlas
Interpreting von Willebrand factor assays: a diagnostic reference guide

Clinical Genetic Testing for VWD
Watch Dr. Jill Johnsen review the clinical applications and interpretation of VWD genetic testing