ADAMTS13 Testing Overview

[…] deficiency plays a key role in the pathogenesis of thrombotic thrombocytopenic purpura ( TTP).1 Clinical Indications for Testing Evaluation of suspected TTP   Distinguishing TTP from […]

TTP – Diagnosis

Suspect diagnosis Suspect diagnosis of immune (acquired) TTP in adults with: Microangiopathic hemolytic anemia (MAHA) Thrombocytopenia New focal neurological findings Prior history of TTP Suspect diagnosis […]

About the Condition

Description/definition: Thrombotic thrombocytopenic purpura ( TTP) is a rare but potentially fatal blood disorder caused by deficiency of von Willebrand factor cleaving protease, called ADAMTS1313, which […]

Management of iTTP

[…] this video lecture, Dr. Flora Peyvandi discusses: The evolution of treatment for immune TTP from plasma exchange alone to a triple regimen including immunosuppression and caplacizumab. […]

TTP in Pregnancy

[…] third trimester and postpartum.18 Many adult-onset cTTP patients experience their first episode of TTP during their first pregnancy.19 ADAMTS13 deficiency (enzyme level 20 About 50% of […]

Transfusion Notes

[…] Platelet transfusions are associated with higher odds of arterial thrombosis and mortality among TTP and HIT patients. Prophylactic platelet transfusions should be avoided in TTP patients, […]

Call for Content: The Blood Project TTP Module

The Blood Project is inviting contributions to our Thrombotic Thrombocytopenic Purpura ( TTP) Module, a one-of-a-kind educational hub that brings together every dimension of this fascinating […]