TPE Demonstration

[…] video: Marlene Healy, RN and Ashley Hallice demonstrate therapeutic plasma exchange (TPE) for TTP on the Spectra Optia, from setup and priming with saline and citrate […]

Hereditary TTP

[…] deficiency, leading to ultra-large vWF multimers, microvascular thrombosis, and hemolytic anemia. Why hereditary TTP can present at any age but is highest-risk in newborns and pregnancy, […]

Rituximab in TTP

Rituximab in thrombotic thrombocytopenic purpura (TTP) Overview: Rituximab is a humanized monoclonal antibody that targets CD20 antigen present on B lymphocytes, leading to depletion of B […]

Caplacizumab and/or Rituximab for TTP

[…] and Haemostasis (ISTH): The ISTH recommends using both rituximab and caplacizumab for acquired TTP, first acute event (conditional recommendation). 2023 British Society of Haematology (BSH): The […]

TTP in Pregnancy

[…] complicates the differential diagnosis of TMAs. The distinguishing features, timing, and urgency of TTP versus preeclampsia/HELLP and complement-mediated HUS, including the role of ADAMTS13 testing. Management […]

Physical Findings in Patients with TTP

[…] image. Want to explore this further? Check out the related sections in our TTP module: TTP – Clinical Presentation TTP – History TTP Clinical Presentation – […]