First-line therapy includes corticosteroids and/or IV immunoglobulin (IVIG [or anti-D immune globulin (anti-D)]. Patients who are not bleeding should be started on steroids (prednisone 1-2 mg/kg up to a maximum of 80 mg daily) or dexamethasone 40 mg PO or IV daily x 3 days. If there is a particularly high risk of bleeding, IVIG may be added to the regimen.
