Acute, severe reaction, typically caused by red blood cell ABO incompatibility.
According to the AABB, acute hemolytic transfusion reaction is defined as the rapid destruction of red blood cells during,
immediately after, or within 24 hours of cessation of transfusion. Clinical and laboratory signs of hemolysis are present.
Criteria for diagnosis:
![](https://www.thebloodproject.com/wp-content/uploads/2022/06/image-87.png)
![](https://www.thebloodproject.com/wp-content/uploads/2022/06/image-88.png)