Jun

14

2022

My patient is taking dabigatran and has a major bleed. What should I do?

By William Aird

A

My patient is taking dabigatran and has a major bleed. What should I do?

  • Consider idarucizumab.
  • Consider oral activated charcoal to prevent further absorption of dabigatran if last dose was taken in the last 2 hours.
  • If idarucizumab is not available, consider:
    • 4-factor PCC or activated PCC (aPCC).
    • Hemodialysis, hemofiltration, or charcoal hemoperfusion to facilitate further clearance of dabigatran, particularly in patients with renal failure.

Stay Updated

If you are interested in getting the latest articles from The Blood Project, enter your name and email

  • This field is for validation purposes and should be left unchanged.