- Consider idarucizumab.
- Consider oral activated charcoal to prevent further absorption of dabigatran if last dose was taken in the last 2 hours.
- If idarucizumab is not available, consider:
- 4-factor PCC or activated PCC (aPCC).
- Hemodialysis, hemofiltration, or charcoal hemoperfusion to facilitate further clearance of dabigatran, particularly in patients with renal failure.