Caplacizumab in TTP
Caplacizumab in thrombotic thrombocytopenic purpura ( TTP) Overview: A humanized, bivalent, variable-domain-only immunoglobulin fragment (Nanobody, Ablynx) directed to the A1 region of von Willebrand factor, which […]
Search Results for ttp
TTP – Classifications
Classifications Thrombotic microangiopathy (TMA): Primary: TTP (see below) Complement-mediated HUS (CM-HUS) – also known as atypical HUS (aHUS) Secondary: Connective tissue disease: Scleroderma renal crisis (SRC) Systemic […]
Multimers, Shear, and ADAMTS13
[…] multimers to persist, increasing the risk of platelet-rich microvascular thrombosis, as seen in TTP. The figure emphasizes that VWF biology is not determined by concentration alone, […]
42 yo M with Hemolytic Anemia and Thrombocytopenia
[…] having bloody diarrhea or diarrhea." Is this story consistent with a diagnosis of TTP? a Yes Combination of bleeding and neurological symptoms is highly characteristic of […]
Journal Club – TTP
[…] thrombocytopenic purpura. Blood. 2011;118(7):1746-1753. Clinical Question In patients with immune thrombotic thrombocytopenic purpura (TTP) is the addition or rituximab to plasma exchange and steroids safe and […]
TTP – Beyond the Guidelines
[…] by Dr. Brian Carney, listen to three leading experts in the field of TTP as they discuss the practical aspects of diagnosis and patient care, from […]
Quiz on TTP Clinical Presentation
What 5 clinical findings make up the classic TTP pentad? Click for Answer Thrombocytopenia Microangiopathic hemolytic anemia Neurologic symptoms Kidney impairment Fever The classic pentad is […]