Knowledge Check

Which of the following condition(s) are associated with increased numbers of polychromatophilic cells on the peripheral smear:

a
Untreated pernicious anemia
b
Autoimmune hemolytic anemia
c
Thrombotic thrombocytopenic purpura
d
Iron deficiency anemia
e
Pyruvate kinase deficiency

True or false: spur cells typically contain a region of central pallor.

a
True
b
False

In assessing a peripheral smear of a patient with a positive direct antiglobulin test (DAT), you find very few platelets.

In which conditions are red cells more hypochromic:

a
Iron deficiency anemia
b
Thalassemia minor

The term “microcytic erythrocytosis” was used in the early 1900s to describe which condition:

a
Iron deficiency anemia
b
Thalassemia minor

What term best characterizes the schematic in panel B (panel A is normal):

a
Hypochromia
b
Hyperchromia
c
Anisocytosis
d
Microcytosis
e
Macrocytosis

What type of poikilocyte is shown above:

a
Teardrop cell
b
Stomatocyte
c
Acanthocyte
d
Sickle cell
e
Heinz body

The term “microcytic erythrocytosis” was used in the early 1900s to describe which condition:

a
True
b
False

What term best characterizes the schematic in panel B (panel A is normal)

a
Hypochromia
b
Hyperchromia
c
Anisocytosis
d
Microcytosis
e
Macrocytosis

Macroovalocytes are typically seen in:

a
Vitamin B12 deficiency
b
Cirrhosis

What type of poikilocyte is shown above:

a
Teardrop cell
b
Stomatocyte
c
Acanthocyte
d
Sickle cell
e
Heinz body

Which panel above is most consistent with warm autoimmune hemolytic anemia:

a
A
b
B
c
C
d
D
e
E

Which lab value(s) is/are likely to be elevated in this patient (more than one answer may apply):

a
AST
b
ALT
c
LDH
d
Haptoglobin
e
Creatinine
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