Mean Corpuscular Hemoglobin (MCH)

The mean corpuscular hemoglobin (MCH). Imagine drilling a hole in the wall of a red blood cell, extracting all the hemoglobin (red color in schematic below) and weighing it… repeat the experiment in many RBCs and then calculate the mean. That would give you the MCH!

Mean corpuscular hemoglobin (MCH) defined as the average weight of Hb per red blood cell (RBC). MCH is not directly measured; it is derived:

MCH = Hb/RBC count

Under normal conditions:

30 x 10-12g = 150 g/L ÷ 5 x 1012/L = 30 picograms

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