Knowledge Check

Thrombosis in heparin-induced thrombocytopenia (HIT) is most common in:

a
Arteries
b
Veins

Venous thrombosis in heparin-induced thrombocytopenia (HIT) is most commonly found in:

a
Legs
b
Brain
c
Arms
d
Adrenal glands

True or false: heparin-induced thrombocytopenia (HIT) is often associated with bleeding, for example in the mucosa of the mouth.

a
True
b
False

True or false: skin lesions in heparin-induced thrombocytopenia (HIT) are due to intradermal microvascular thromboses.

a
True
b
False

Sinha et al:

The adrenal glands in particular are at a higher risk of injury due to heparin-induced thrombocytopenia, due to their vascularity. The vascular supply to each adrenal gland is drained by a single central adrenal vein, which is highly susceptible to outflow obstruction. The systemic thrombosis caused by heparin-induced thrombocytopenia can cause adrenal vein thrombosis which subsequently leads to arterial adrenal gland hemorrhage and eventual life-threatening adrenal crisis.

Cureus. 2021 Feb 16;13(2):e13374.