Knowledge Check • The Blood Project

How is neutrophil hypersegmentation generally defined?

Click for Answer

1% neutrophils with 6 lobes or 5% with 5 lobes

What are causes of macrocytosis?

a

Alcohol

b

Hypothyroidism

c

Pancreatitis

d

Hydroxyurea

e

Chronic liver disease

Which tests may be abnormal in vitamin B12 deficiency?

a

Haptoglobin

b

LDH

c

Hypersegmented neutrophils

d

Serum vitamin B12

e

ALT

Vitamin B12 deficiency is diagnosed by showing a low serum vitamin B12 level (<200 ng/L). What test would order if the vitamin B12 level was low-normal in a patient you suspected vitamin B12 deficiency in?

What test would you like to order?

Click for Answer

Serum methylmalonic acid

Which test is most specific for diagnosis of pernicious anemia?

a

Anti-intrinsic factor antibodies

b

Anti-parietal cell antibodies

True or false: the only route for effectively administering vitamin B12 is intramuscular.

a

True

b

False