Dr. Zheng is the Russel J Eilers Professor and Chair of Pathology and Laboratory Medicine at the University of Kansas Medical Center, Kansas City, Kansas. Following completion of his pathology residency and transfusion medicine fellowship at Barnes-Jewish Hospital, Washington University in St. Louis, Dr. Zheng was appointed as assistant professor of pathology at the University of Pennsylvania and medical director of coagulation laboratory at Children’s Hospital of Philadelphia. Subsequently, Dr. Zheng was recruited to the University of Alabama at Birmingham as Division Director of Laboratory Medicine and more recently to the University of Kansas Medical Center as the Chair of Pathology and Laboratory Medicine.
Dr. Zheng was among the first group of scientists who identified and cloned ADAMTS13, a plasma metalloprotease that cleaves von Willebrand factor. Over the past decades, Dr. Zheng’s laboratory has made seminal contributions towards our understandings of the structure-function and regulation of ADAMTS13 protease, and pathogenesis of thrombotic thrombocytopenic purpura (TTP), as well as other inflammatory thrombotic disorders associated with imbalance of ADAMTS13/VWF axis. Dr. Zheng’s research group have published more than 130 manuscripts in various high profile and peer reviewed journals, including five high quality textbook chapters. Dr. Zheng led an internal group of experts to develop and publish the first ISTH guidelines for diagnosis and management of TTP. Dr. Zheng also serves in the leadership roles in many professional societies, editorial boards, and various study sections of National Institute of Health.