Chantal Séguin

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Chantal Séguin, MD is an Associate Professor in the Department of Medicine, Division of Hematology and Oncology at The McGill University Health Center, and a Clinician Investigator in the Bone Engineering and Vascular Biology Research Lab at the Research Institute of the McGill University Health Centre (RI-MUHC) in Montreal, QC. She has completed a fellowship in endothelial cell biology at the Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, under the supervision of William C. Aird, M.D. Since her return to McGill University, she has been involved in teaching hematology with an emphasis on blood coagulation and thrombosis. Her main focus of research involves the study of the endothelial and vascular complications following cancer therapy as well as active clinical research on venous thrombosis, including thrombosis in the cancer population. Also, Chantal has developed an endothelial cell-based approach to osteonecrosis of the femoral head, a vascular complication seen frequently in patients affected with acute lymphoblastic leukemia as a result of high dose glucocorticoids. She also identified a novel gain-of-function mutation in TRPV4 in patients affected with inherited osteonecrosis of the femoral head.