Labs and Quiz
[…] patient with thrombocytopenia, it is imperative to rule out thrombotic thrombocytopenic purpura ( TTP) in such patients, especially if they have anemia. TTP is a potentially […]
[…] patient with thrombocytopenia, it is imperative to rule out thrombotic thrombocytopenic purpura ( TTP) in such patients, especially if they have anemia. TTP is a potentially […]
[…] (for example, 1 mg/kg/day) and (in some cases) rituximab or caplacizumab; for secondary TTP, same treatment as with primary TTP in addition to treatment of the […]
[…] caplacizumab and immunosuppression without the addition of therapeutic plasma exchange (TPE)? Background Immune TTP is a condition defined by loss of the functional protease ADAMTS13 due […]
[…] is guidance. Combined cytopenias are especially prone to diagnostic overreach. Labels like “ TTP,” “DIC,” “marrow failure,” or “bone marrow biopsy needed” can propagate quickly and […]
What protease is deficient in TTP? Click for Answer ADAMTS13 What is the normal function of ADAMTS13 Click for Answer Cleaves ultra-large vWF multimers, which are […]
[…] the differential diagnosis to a thrombotic microangiopathy (TMA), including thrombotic thrombocytopenia purpura ( TTP), hemolytic uremic syndrome (HUS) or disseminated intravascular coagulation (DIC). Can the number/frequency […]
[…] State University. Dr. Cataland’s clinical and research interests include thrombotic thrombocytopenic purpura ( TTP) and atypical hemolytic uremic syndrome (aHUS) with an emphasis on immune-mediated TTP […]