Oct

6

2021

What is thrombotic thrombocytopenic purpura (TTP)?

By William Aird

A

What is thrombotic thrombocytopenic purpura (TTP)?

A thrombotic microangiopathy (TMA) caused by deficiency of ADAMTS13, a von Willebrand factor cleaving protease, which leads to platelet-mediated occlusion of microvessels, thrombocytopenia, microangiopathic hemolytic anemia, and widespread multiorgan thrombosis and injury.

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