Fresh frozen plasma (FFP) is plasma that is prepared from a whole blood or apheresis collection and frozen at –18 C or colder within the time frame as specified in the manufacturer’s instructions for use of the blood collection, processing, and storage system (typically within 8 hours of phlebotomy):
- On average, units contain 200 to 250 mL, but apheresis-derived units may contain as much as 400 to 600 mL. FFP contains plasma proteins, including all coagulation factors.
- FFP contains normal levels of the labile coagulation factors, factors V and VIII.
- FFP should be infused immediately after thawing or stored at 1 to 6 C. After 24 hours, the component must be discarded or, if collected in a functionally closed system, may be relabeled as thawed plasma.
Plasma must be ABO compatible with the recipient’s red cells. Compatibility with RhD is not necessary in plasma transfusion. Compatibility tests prior to transfusion are not necessary.
FFP serves as a source of plasma proteins for patients who are deficient in or have defective plasma proteins.
Read more here.