Jul

5

2022

What is a lupus anticoagulant?

By William Aird

  • Detects all antiphospholipid antibodies.
  • Two tests with distinct performance principles are needed, typically:
    • dRVVT
    • aPTT, typically silica-based
  • Three-step procedure:
    • Screening
    • Mixing
    • Confirmation

LA should be considered positive if one of the two test systems gives a positive result in the three steps (screen-mix-confirm). Learn more here.