- Conditions involving macrophage-mediated ingestion or red cells:
- Hemophagocytic lymphohistiocytosis (HLH)
- Pernicious anemia
- Resorbing hematoma
- Conditions not associated with red cell destruction:
- Cirrhosis may also mimic hemolysis because the liver is responsible for synthesizing haptoglobin and hepatocytes release LDH, and AST may be elevated disproportionately to ALT, especially in alcoholic liver disease.