Sep

20

2021

What is the differential diagnosis of neutrophilia?

By William Aird

Reactive (secondary):

  • Infection
  • Chronic inflammation
  • Smoking
  • Stress
  • Obesity
  • Drugs, for example:
    • Corticosteroids
    • Beta-agonists
    • Lithium
    • Epinephrine
  • Endocrine disorders:
    • Hypercortisolism
    • Thyroid storm
    • Pre-eclampsia
  • Post-splenectomy state
  • Bone marrow stimulation
  • Nonhematologic malignancy
  • Inherited disorders

Clonal (primary):

  • Chronic neutrophilic leukemia
  • Chronic myelogenous leukemia
  • Essential thrombocytosis (ET)
  • Polycythemia vera