- Increased calcium (serum calcium > 1 mg/dL [0.25 mmol/L]
- Renal insufficiency (creatinine clearance 2 mg/dL [177 mcmol/L])
- Anemia (hemoglobin > 20 g/L [2 g/dL] below lower limit of normal or hemoglobin < 100 g/L [10 g/dL])
- Bone lesions (≥ 1 osteolytic lesions on skeletal radiography, computed tomography [CT], or positron emission tomography [PET]-CT)
Sep
18
2021