Less avascular necrosis, pulmonary hypertension, leg ulcers, and stroke; more retinopathy. 0.4% painful crises per patient year in those with HbSC, less than half the rate in sickle cell anemia. Learn more here.
Complication | HbSC | HbSS |
---|---|---|
Avascular necrosis | + | +++ |
Pulmonary hypertension | + | +++ |
Leg ulcers | + | +++ |
Stroke | + | +++ |
Retinopathy | +++ | + |
Painful crises | + | +++ |