Jun

22

2022

What are first-level tests for diagnosing von Willebrand disease (vWD)?

By William Aird

  • von Willebrand factor antigen (vWF:Ag)
  • von Willebrand factor ristocetin cofactor activity (vWF:RCo) (platelet-binding activity of vWF measured by vWF:RCo assay)
  • Factor VIII activity (FVIII:C)
  • von Willebrand factor collagen binding (vWF:CB) activity (recommended by BCSH but not NHLBI as first-level test)