Oct

7

2021

What are causes of congenital secondary erythrocytosis?

By William Aird

  • Changes in hemoglobin oxygen affinity, for example high-affinity hemoglobin mutations.
  • Mutations in oxygen sensing/hypoxia-inducible factor (HIF) signaling pathway, for example Chuvash polycythemia (mutation in VHL gene, automosomal recessive).

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