How should I start vitamin K antagonist (VKA) therapy in patient with venous thromboembolism (VTE)?

Start initial treatment with parenteral anticoagulation. Administer VKA early (for example, same day as start of parenteral therapy) and continue parenteral anticoagulation for ≥ 5 days and until INR is ≥ 2 for at least 24 hours. Learn more here.