Summary of 47 platelet proteomics studies. A, Platelet proteomics has been used to characterize the global proteome, specific subproteomes, activity-based protein profiling (ABPP), and post-translational modifications (PTM).B, These studies are mainly (40%) based on 2-dimensional gel electrophoresis (2-DE)/difference gel electrophoresis (DIGE),whereas gel-free methods (23%) are still under-represented. Combination refers to studies using 2-DE/DIGE in combination with other approaches. COFRADIC indicates combined fractional diagonal chromatography; and MudPIT, multidimensional protein identification technology. Source.
