How do we dose von Willebrand factor (vWF) concentrate in patients with von Willebrand disease (vWD)?

1 unit vWF:RCo/kg infused will result in recovery of 1.5-2 units vWF:RCo/dL in adults; 50 units vWF:RCo/kg will give a recovery of 75-100 units vWF:RCo/dL.