How do drugs cause hemolysis?

Q: How do drugs cause hemolysis?

Immune-mediated : drugs act as haptens or induce autoantibodies that target RBCs (e.g., penicillin, methyldopa). Oxidant stress : in G6PD deficiency, certain drugs (e.g., sulfa drugs, dapsone) trigger hemolysis by overwhelming RBC antioxidant defenses.

Q: How do drugs cause hemolysis?

Immune-mediated : drugs act as haptens or induce autoantibodies that target RBCs (e.g., penicillin, methyldopa). Oxidant stress : in G6PD deficiency, certain drugs (e.g., sulfa drugs, dapsone) trigger hemolysis by overwhelming RBC antioxidant defenses.

By William Aird

How do drugs cause hemolysis?

Immune-mediated: drugs act as haptens or induce autoantibodies that target RBCs (e.g., penicillin, methyldopa).
Oxidant stress: in G6PD deficiency, certain drugs (e.g., sulfa drugs, dapsone) trigger hemolysis by overwhelming RBC antioxidant defenses.

Posted on October 1, 2025

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