Nov

11

2021

Can factor XIII deficiency be diagnosed with routine coagulation labs such as a prothrombin time (PT) or activated partial thromboplastin time (aPTT)?

By William Aird

A

Can factor XIII deficiency be diagnosed with routine coagulation labs such as a prothrombin time (PT) or activated partial thromboplastin time (aPTT)?

No, factor XIII deficiency cannot be detected by routine clotting tests such as PT, aPTT, or thrombin time. Rather, it is detected by ammonia release or amine incorporation assays.

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