C. perfringens can cause massive hemolysis. What is C. perfringens?

By William Aird

C. perfringens is an anaerobic, gram-positive rod. It is a normal inhabitant of the human bowel and genital tract. C. perfringens septicemia is an uncommon but usually fatal condition following clostridial infection mostly from the uterus, colon or biliary tract. In general C. perfringens septicemia is seen in patients with underlying malignancy or diabetes mellitus, or in otherwise healthy individuals with recent abdominal surgery or following abortion.

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