TTP Quiz – Part 4

TTP is a thrombotic microangiopathy caused by a deficiency of ___ which results in thrombocytopenia, microangiopathic hemolytic anemia, and widespread multiorgan thrombosis and injury. Fill […]

Post-Discharge Care

Prev1/94Next About this Module Thalassemia TTP Module Cold Agglutinin Disease Overview & Orientation Co-Editors Welcome What is a Topic Module? Introduction Definitions & Core Concepts Navigating […]

Peripheral Smears

Prev1/94Next About this Module Thalassemia TTP Module Cold Agglutinin Disease Overview & Orientation Co-Editors Welcome What is a Topic Module? Introduction Definitions & Core Concepts Navigating […]

Quiz on TTP Classification

Name the 2 major types of TTP Click for Answer Acquired (immune) Congenital What is the difference between primary and secondary immune/acquired TTP (just one answer […]

Pathophysiology of TTP

[…] cloning of ADAMTS13 revealed that impaired cleavage of ULVWF drives microvascular thrombosis in TTP. The distinction between congenital TTP caused by ADAMTS13 mutations and immune-mediated TTP […]

Journal Club – TTP

[…] Med. 2019; 380(4): 335-346. Clinical Question: In patients with thrombotic thrombocytopenic purpura ( TTP), does addition of caplacizumab to plasma exchange improve time to normalization of […]

Coach’s Corner

[…] 1 Background: The ISTH guidelines for the diagnosis of thrombotic thrombocytopenic purpura ( TTP) recommends assessing the pretest probability of TTP using clinical assessment (gestalt) and/or […]