|Presence of platelet clumps (size not specified) on peripheral smear
|In addition to anti-platelet antibodies, platelet clumping may be caused by pre-analytic errors such as over-filled or under-filled EDTA tubes, clotted specimens, or a time delay between sample collection and testing.
|Conditions associated with the process
|Platelet clumping may lead to erroneous platelet count
|Platelet clumping is most commonly caused by pre-analytic errors such as improper or delayed sample mixing, clotted sample, over-filled or underfilled tubes, and time delay between sample collection and testing. It can also be an ex vivo phenomenon due to EDTA-dependent antibodies. Occasionally this may occur in due to infections, drugs, cold agglutinins or immunoglobulins.
|First reported in 1969
|Reviewed and edited by
|J Clin Med 2021;10:594