|Red blood cell, shape abnormality
|Fish-shaped red cell
|Also known as
|Similar to tear-drop cells, fish-shaped cells have one round and one tapered end. In contrast to teardrop cells, the tapered end flares out into two buds, causing the appearance of fish’s tail.
|Conditions associated with the shape abnormality
|Not observed in peripheral blood smears of healthy persons; found in hereditary elliptocytosis, iron deficiency anemia, lymphoproliferative disorders and myelofibrosis. The number of fish-shaped red cells on a smear has been significantly associated with severity of anemia.
|Mechanism of formation
|Reviewed and edited by
|Clin Chem Lab Med. 2018;56:323