Knowledge Check
Sort lab test (top) according to whether it is typically altered in TTP or not (bottom):
Low ADAMTS13
Schistocytes on smear
Increased reticulocytes
Stool positive for Shiga toxin
Positive DAT
Low haptoglobin
Spur cells in smear
Elevated ALT
Elevated LDH
Elevated PT and/or aPTT
Elevated ADAMTS13
Elevated direct bilirubin
Elevated AST
Altered in TTP
Not altered in TTP
Abbreviations: TTP, thrombotic thrombocytopenic purpura; LDH, lactate dehydrogenase; DAT, direct antiglobulin test; PT, prothrombin time; aPTT, activated partial thromboplastin time.
