Knowledge Check
Sort lab test (top) according to whether it is typically altered in TTP or not (bottom):
Elevated AST
Spur cells in smear
Positive DAT
Stool positive for Shiga toxin
Increased reticulocytes
Elevated ADAMTS13
Elevated PT and/or aPTT
Elevated ALT
Low ADAMTS13
Elevated direct bilirubin
Elevated LDH
Schistocytes on smear
Low haptoglobin
Altered in TTP
Not altered in TTP
Abbreviations: TTP, thrombotic thrombocytopenic purpura; LDH, lactate dehydrogenase; DAT, direct antiglobulin test; PT, prothrombin time; aPTT, activated partial thromboplastin time.
