Clue: Increased fragility

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Name 2 possible diagnoses for the above smear

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Hereditary spherocytosis
Warm autoimmune hemolytic anemia

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What cell type are the yellow arrows pointing to?

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Spherocyte

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What cell type is the green arrow pointing to?

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Polychromatophilic cell

Hemolysis in this patient is primarily:

a

Intravascular

b

Extravascular

Assume that the Coombs test came back positive for IgG and the patient had a platelet count of 5 x 10⁹/L.

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What condition would you consider?

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Evans syndrome

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