Knowledge Check

Which of the following factors has/have been shown to influence platelet counts:

a
Gender
Counts are higher in men than women.
b
Genetics
c
Age
Platelet count decreases with age.
d
Weight

True of false: immune thrombocytopenia requires a platelet count < 150 x 109/L.

a
True
b
False
< 100 x 10^9/L

True of false: the diagnosis of essential thrombocythemia requires a platelet count > 450 x 109/L.

a
True
b
False

One study examined the long-term outcome of otherwise healthy individuals with an incidentally discovered platelet count of 100-150 x 109/L. Which of the following observations was/were made:

a
Most of the patients experienced a fall in platelet count < 100 x 10^9/L
b
Most patients maintained a platelet count > 100 x 10^9/L
c
Most patients developed ITP

Which of the following statements(s) is/are correct regarding adoption of personalized reference intervals for platelet counts:

a
Fewer patients with thrombocytopenia would be unduly diagnosed
b
More patients with thrombocytopenia would be unduly diagnosed
c
Fewer patients with thrombocytosis would be diagnosed
d
More patients with thrombocytosis would be diagnosed
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