Microcytic Anemia: Test Your Understanding
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What does a low MCV usually mean?
a
Your red blood cells are larger than normal
Larger cells correspond to high MCV (macrocytosis).
b
Your red blood cells are smaller than normal
Correct — a low MCV means the red blood cells are smaller than normal.
c
You are dehydrated
Dehydration affects plasma levels, not cell size.
d
You definitely have anemia
Many people have a low MCV without anemia.
Which is the most common cause of microcytic anemia?
a
Vitamin B12 deficiency
B12 deficiency causes large cells.
b
Iron deficiency
Correct — iron deficiency is by far the most common cause.
c
Kidney disease
Typically causes normocytic anemia.
d
Liver disease
Typically causes normocytic anemia.
A person has a low MCV but a normal hemoglobin level. What is the most likely explanation?
a
Early iron deficiency
Correct — early or mild iron deficiency may lower the MCV before the hemoglobin drops.
b
Severe anemia
If hemoglobin is normal, anemia is not present.
c
A dangerous bone marrow disorder
Serious marrow disorders rarely present with isolated low MCV.
d
Dehydration
Dehydration does not change MCV.
Which condition often causes lifelong small red blood cells but usually requires no treatment?
a
Thalassemia trait
Correct — thalassemia trait causes small red blood cells but is benign and does not need treatment.
b
Acute blood loss
c
Hemolysis
d
Severe iron deficiency
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