Knowledge Check

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True or false: We normally have a small amount of methemoglobin in our red blood cells.

a
True
b
False

What is a normal range of MetHb?

a
1%
b
5%
c
10%
d
20%

What is the state of iron in MetHb?

a
1+
b
2+
c
3+
d
4+

Which enzyme plays the most important role in reducing methemoglobin back to normal hemoglobin:

a
Nicotinamide adenine dinucleotide (NADH) cytochrome b5 reductase (Cyb5R):
b
NADPH-dependent methemoglobin reductase
c
Catalase
d
G6PD
e
Pyruvate kinase

Which statement(s) is/are true in methemoglobinemia:

a
Pulse oximetry does not detect MetHb
b
Oxygen saturation measured by pulse oximeter is about 85%
c
Administration of supplemental oxygen normalizes the oxygen saturation
d
Hemolytic anemia may be present
e
The blood is bright blue in color

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