Macrocytic Anemia: Test Your Understanding
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What does a high MCV usually mean?
a
Your red blood cells are larger than normal
Correct — MCV reflects average red blood cell size; a high MCV means the cells are larger, not that the condition is dangerous.
b
You definitely have leukemia
A high MCV is not a sign of leukemia.
c
You need an urgent bone marrow biopsy
Most people with macrocytosis do not need a biopsy.
Which of the following is a common and treatable cause of macrocytic anemia?
a
Vitamin B12 deficiency
Correct — B12 deficiency is one of the best-known causes and is often easy to treat.
b
Kidney failure
Kidney disease usually causes normocytic anemia.
c
High blood pressure
Blood pressure does not affect MCV.
d
Mild dehydration
Dehydration affects plasma levels, not red cell size.
Which symptom is most specifically associated with vitamin B12 deficiency?
a
Cough
b
Numbness or tingling in hands or feet
Correct — B12 deficiency can cause nerve symptoms such as tingling or balance problems.
c
Fever
d
Abdominal bloating
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