Knowledge Check

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Which of the following statement(s) is/are correct concerning anemia of chronic kidney disease:

a
It is rare
b
It is caused caused by absolute, not functional iron deficiency
c
It is caused caused by functional, not absolute iron deficiency
d
It is caused by both absolute and functional iron deficiency

Which of the following statement(s) is/are correct concerning absolute iron deficiency in anemia of chronic kidney disease:

a
It is most commonly caused by increased blood loss
b
It may also caused by decreased iron intake and absorption
c
It is associated with reduction or loss of total body iron stores
d
It is associated with increased iron in tissue macrophages

Which of the following statement(s) is/are correct concerning functional iron deficiency in anemia of chronic kidney disease:

a
It is associated with depletion of storage iron in tissue macrophages
b
It is associated with normal or increased iron stores in tissue macrophages
c
It is associated with reduced availability of iron for erythropoiesis
d
It is mediated primarily by increased levels of hepcidin

True of false: thresholds of ferritin and transferrin at which iron stores are deficient are higher in patients with CKD compared to those without CKD.

a
True
b
False

True of false: patients with anemia of CKD may respond to iron therapy (increased Hb) even when they have stainable iron in the bone marrow.

a
True
b
False

Match the serum ferritin (ng/ml) threshold for diagnosing iron deficiency according to patient population:

30
100
200
Inflammation or non-dialysis CKD
No inflammation, no CKD
CKD on dialysis
Correct! Sorry, Incorrect.

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