Hereditary Spherocytosis: Test Your Understanding
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What is hereditary spherocytosis?
a
A type of blood cancer
b
A condition where red blood cells are shaped differently and break down early
Hereditary spherocytosis is a genetic condition in which red blood cells are more round (spherocytes) than usual, making them more likely to be removed early, especially by the spleen.
c
A vitamin deficiency
d
An infection of red blood cells
Why can hereditary spherocytosis cause anemia?
a
The bone marrow stops making red blood cells
b
Red blood cells break down faster than normal
c
Iron cannot be absorbed
d
Red blood cells break down faster than normal
In hereditary spherocytosis, red blood cells have a shorter lifespan, which can lead to anemia if the body cannot fully keep up with replacement.
Which symptom is commonly associated with hereditary spherocytosis?
a
Frequent infections
b
Yellowing of the eyes or skin (jaundice)
Because red blood cells break down earlier, bilirubin levels can rise, leading to jaundice. Some people may also develop gallstones.
c
Severe bleeding
d
High blood pressure
Is hereditary spherocytosis always severe?
a
Yes, it is always life-threatening
b
Yes, treatment is always required
c
No, severity ranges from very mild to more significant
Hereditary spherocytosis has a wide range of severity. Many people have mild disease and live normal lives with monitoring alone.
d
Only children are affected
How is hereditary spherocytosis usually managed?
a
With chemotherapy
b
With regular blood transfusions for everyone
c
With monitoring, and treatment only if symptoms are significant
Management depends on severity. Many patients need only monitoring, while others may require treatments such as folic acid, transfusions during illness, or spleen-related interventions in selected cases.
d
With antibiotics
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