Knowledge Check

True or false: most physical finings in hereditary hemochromatosis arise from the effects of excessive iron deposition on organ function.

a
True
b
False

True or false: The heart is spared in hereditary hemochromatosis (HH).

a
True
b
False
Cardiac hemochromatosis or primary iron-overload (dilated) cardiomyopathy, while relatively rare in HH, is an important and potentially preventable cause of heart failure. Cardiac hemochromatosis causes a dilated cardiomyopathy with dilated ventricles, low left ventricular ejection fraction (LVEF), and decreased fractional shortening.

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