Knowledge Check

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True of false: D-dimers are a type of fibrin degradation product.

a
True
b
False

D-dimers derived from:

a
The action of thrombin on cross-linked fibrin
b
The action of plasmin on cross-linked fibrin
c
The action of plasmin on fibrinogen

True or false: FXIII activity is required for ultimate formation of D-dimers.

a
True
b
False

True or false: D-dimers are insoluble.

a
True
b
False

True or false: D-dimers are not detectable in a normal person’s blood.

a
True
b
False

True or false: elevated D-dimers only arise when there is intravascular clot formation.

a
True
b
False

What is the correct workflow in a patient with suspected VTE:

a
Imaging followed by clinical score followed by D-dimer level
b
D-dimer level followed by clinical score followed by imaging
c
Clinical score followed by imaging followed by D-dimer
d
Clinical score followed by D-dimer followed by imaging

True or false: D-dimer levels are included in diagnostic scores for DIC.

a
True
b
False
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