Check Your Understanding – Type 2 VWD
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What is the main feature of Type 2 von Willebrand disease?
a
The body makes no von Willebrand factor.
b
The body has lower-than-normal platelet counts.
c
Von Willebrand factor is present, but it does not work properly.
Type 2 von Willebrand disease is a qualitative problem. The body usually makes von Willebrand factor, but the protein does not function normally, making it less effective at helping blood clot.
d
Red blood cells break down too quickly.
Why are there different subtypes of Type 2 von Willebrand disease?
a
They describe different blood types.
b
They describe different ways that von Willebrand factor can malfunction.
Type 2 von Willebrand disease includes several subtypes (2A, 2B, 2M, and 2N) because von Willebrand factor can function abnormally in different ways. Identifying the subtype helps guide treatment.
c
They describe different stages of the disease.
d
They describe how long someone has had the condition.
Which statement about treatment for Type 2 von Willebrand disease is TRUE?
a
The best treatment depends on the specific Type 2 subtype and the clinical situation.
Different Type 2 subtypes behave differently. Some people respond to desmopressin (DDAVP), while others need von Willebrand factor replacement or other treatments. Your subtype helps guide these decisions.
b
Everyone with Type 2 responds well to desmopressin (DDAVP).
c
Treatment is the same for every subtype.
d
Daily treatment is required for everyone.
Why might additional blood tests be needed after Type 2 von Willebrand disease is suspected?
a
Because one blood test usually cannot identify the specific subtype.
Doctors often perform additional laboratory tests to determine the specific Type 2 subtype. This information helps choose the safest and most effective treatment.
b
Because the first blood test is usually incorrect.
c
Because treatment always changes the diagnosis.
d
Because surgery is required before a diagnosis can be made.
Which statement best describes the outlook for most people with Type 2 von Willebrand disease?
a
Everyday life is usually impossible without treatment.
b
Most people can live full, active lives with the right planning and treatment when needed.
Although bleeding risk varies among the different Type 2 subtypes, most people live normal, active lives. Planning ahead for procedures and using the right treatment when needed help reduce bleeding risk.
c
Type 2 always becomes more severe over time.
d
Blood transfusions are usually needed throughout life.
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