Knowledge Check
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Duffy-null associated neutrophil count (DANC) is associated with a polymorphism in what gene?
Click for AnswerDuffy was named in 1950 after:
a
The physician who discovered it
b
The patient in whom it was discovered
c
None of the above
True or false: on average, white blood cell counts are lower in people with African ancestry compared to Caucasians.
a
True
b
False
True or false: all individuals who are Duffy null have neutropenia.
a
True
b
False
About 10%
Which statement(s) is/are true concerning individuals with DANC:
a
Asymptomatic
b
Increased risk of infection
c
Protection against malarial infection
d
Increased risk of anemia and/or thrombocytopenia
Which statement(s) is/are true concerning expression of Ackr1 in Duffy-null individuals (i.e., those with DANC):
a
Loss of expression in RBCs and endothelial cells
b
Selective loss of expression in RBCs
c
No loss of expression in RBCs or endothelial cells
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