What is andexanet alfa?Click for Answer
Andexanet alfa may be used to reverse which of the following DOACs?
Correct. Rivaroxaban is a factor Xa inhibitor.
Dabigatran inhibits thrombin, not factor Xa.
Correct. Apixaban is a factor Xa inhibitor.
Andexanet alfa is a modified version of factor Xa that has been mutated at two key sites.
What 2 activities of FXa are affected by these mutations?Click for Answer
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