Knowledge Check

Which of the following statements about testosterone therapy is/are true:

a
Has a dose-dependent stimulating effect on erythropoiesis
b
Oral formulations have the highest risk of erythrocytosis
c
Testosterone-induced erythrocytosis may occur within months of therapy
d
Testosterone-induced erythrocytosis has been shown to increase the risk of thrombosis

2 RBC units are requested for a 65-year-old female with a history of mitral valve regurgitation scheduled to have elective mitral valve replacement replacement who was found to have a Hb level of 7.5 g/dL. True or false: the order for the RBC transfusion is appropriate.

a
True
b
False
More information is needed. In a non-acute setting, for elective surgeries, anemia should be investigated and treated. If the surgery cannot be postponed, patient can be transfused one unit. There is no need to transfuse two units pre-operatively, however, she might need more units during the surgery.
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