Knowledge Check • The Blood Project

What are causes of microcytosis?

a

HbCC

b

HbEE

c

Beta-thalassemia

d

Alpha-thalassemia

e

Chronic kidney disease

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1. Target cells
2. Irregularly contracted cells

True of false: HbCC is associated with reduced mean corpuscular hemoglobin concentration (MCHC).

a

True

b

False

HbCC is associated with elevated MCHC.

Sort the cause of anemia according to whether the red blood cells are typically small (microcytic) or large (macrocytic):

Alcohol

Hydroxyurea

Anemia of inflammation

Iron deficiency

Vitamin B12 deficiency

Hb E disorders

Hb C disorders

Lead poisoning

Microangiopathic hemolytic anemia

Hypothyroidism

Thalassemia

Liver disease

Microcytic

Macrocytic